🧬 What Is TB‑500? A Peptide Studied for Tissue Growth and Cell Migration

What Is TB‑500?

TB‑500 is a synthetic peptide that is studied for its similarity to a naturally occurring protein called Thymosin Beta‑4 (Tβ4). Thymosin Beta‑4 is found in almost all human and animal cells and is known to play a role in cell migration, wound response, and tissue organization.

TB‑500 is the synthetic version of a specific short fragment of Thymosin Beta‑4 that is thought to be responsible for many of its biological activities. It has become a focus in scientific studies exploring how tissues respond to injury, inflammation, and stress.

Explore TB‑500 at NovaGene Labs →

Why Is TB‑500 Studied?

In research settings, TB‑500 is being explored for its potential roles in supporting:

  • Tissue regeneration models
  • Cell migration and motility
  • Angiogenesis (formation of new blood vessels)
  • Inflammatory response signaling
  • Wound modeling and extracellular matrix remodeling

Scientists are particularly interested in TB‑500’s interactions with actin, a protein involved in the structure and movement of cells. By binding to actin, TB‑500 may influence how cells move and organize themselves during repair processes.

How Does TB‑500 Work in Research?

Studies suggest that TB‑500 may help regulate the movement of cells to damaged or inflamed areas. It’s often examined in vitro or in animal models for its:

  • Role in actin-binding and reorganization
  • Ability to promote new blood vessel formation
  • Modulation of cytokine activity (signaling proteins in inflammation)
  • Involvement in connective tissue support

Researchers have also evaluated its potential role in soft tissue, muscle, and tendon models to observe cell-level responses during simulated stress and damage.

Why Choose NovaGene Labs?

NovaGene Labs provides high-quality TB‑500 for research institutions and laboratories looking to investigate peptide function under controlled conditions.

Our TB‑500 is:

  • Produced under stringent lab conditions
  • Available in lyophilized and solution formats
  • Cold-shipped only when pre-mixed (lyophilized products are not shipped cold)
  • Clearly labeled for Research Use Only

View TB‑500 Research Product →

Disclaimer: All products sold by NovaGene Labs are intended strictly for Research Use Only. For more details, please visit our RUO policy: Read More →

📚 References

  • Huff, T. et al. (2001). Structure and function of thymosin beta‑4. Cell and Molecular Life Sciences, 58(12–13), 1963–1969.
  • Goldstein, A. L. et al. (2005). Thymosin beta‑4 and tissue repair. Annals of the New York Academy of Sciences, 1051(1), 238–247.
  • Philp, D. et al. (2004). Thymosin beta‑4 promotes dermal healing. Journal of Investigative Dermatology, 123(2), 371–378.
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