☀️ What Is MT‑2? A Peptide Studied for Pigmentation and Photoprotection
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What Is MT‑2?
MT‑2, short for Melanotan II, is a synthetic peptide analog of the naturally occurring hormone alpha-melanocyte-stimulating hormone (α‑MSH). It is widely studied in preclinical environments for its ability to activate melanocortin receptors, which are involved in skin pigmentation, energy homeostasis, and immune signaling.
MT‑2 is of interest in cellular and molecular research exploring melanogenesis (the process that produces melanin), as well as photoprotective responses in tissue models exposed to ultraviolet (UV) light.
Explore MT‑2 at NovaGene Labs →
Why Do Researchers Study MT‑2?
MT‑2 is commonly used in lab settings to investigate:
- Melanin production and pigmentation signaling
- Melanocortin receptor activity (especially MC1R and MC4R)
- UV response in skin cell models
- Photoprotection and oxidative stress
- Neuroendocrine signaling pathways
- Appetite and metabolism regulation (via MC4R)
Though most research centers on melanogenesis, MT‑2 is also studied in neural models because it interacts with receptors found in the central nervous system.
How MT‑2 Functions in Research
MT‑2 works by binding to melanocortin receptors, especially MC1R in skin cell research, where it stimulates melanin production. In laboratory models, this is often used to simulate tanning-like responses or to assess protective responses against UV-induced oxidative damage.
It is also studied for its activity at MC3R and MC4R, which have been implicated in research related to appetite control, metabolism, and energy balance.
Why Choose NovaGene Labs?
NovaGene Labs offers high-purity MT‑2 for authorized laboratories and institutions conducting preclinical and biochemical research.
Our MT‑2 is:
- Synthesized under strict lab protocols
- Offered in both lyophilized and solution formats
- Cold-shipped only when pre-mixed (lyophilized products are not shipped cold)
- Clearly labeled for Research Use Only
📚 References
- Wakamatsu, K. et al. (2006). Diversity of pigmentation in human skin melanocytes. Pigment Cell Research, 19(3), 154–162.
- Hadley, M. E. et al. (1996). Melanocortin receptors: their physiological roles and therapeutic potential. Journal of Investigative Dermatology, 106(1), 179–182.
- Cone, R. D. (2005). Anatomy and regulation of the central melanocortin system. Nature Neuroscience, 8(5), 571–578.